Who may benefit?
- Women over the age of 38 years, as it has been shown that zona tend to thicken and harden with age.
- Patients with a history of previous failure to become pregnant following IVF with good quality embryos.
- Frozen embryo replacement cycles, as it has been shown that zona tend to harden during the freezing and thawing process.
- Patients with increased FSH levels.
- Women who have eggs with thick zona.






